COVID-19/SARS-CoV-2 Data in PubChem

This page contains a compiled list of PubChem data related to COVID-19 (Coronavirus Disease 2019) and SARS-CoV-2 (Severe acute respiratory syndrome coronavirus 2).

PubChem is part of the National Center for Biotechnology Information (home of GenBank, PubMed, PMC, ClinicalTrials.gov and many other resources) at the National Library of Medicine (NLM), one of the institutes at the U.S. National Institutes of Health (NIH).
 

Select lists of records in PubChem with COVID-19 related information:

• Compounds
  • Compounds used in SARS-CoV-2 clinical trials
  • Compounds found in COVID19-related PDB structures
  • Coronavirus Studies: 
    • PubChem created a "Coronavirus Studies" evidence section on each compound summary page for those involved with coronavirus and related studies both in vivo and in vitro. This section provides aggregated reference information from PubMed, PDB, ClinicalTrials.gov, Springer Nature, IUPHAR/BPS Guide to PHARMACOLOGY, and DrugBank published since November 2019. The section can be found under the Literature heading when available. An example page is: https://pubchem.ncbi.nlm.nih.gov/compound/Remdesivir#section=Coronavirus-Studies
    • Additional clinical studies can be found in the Clinical Trails section when available, e.g.  https://pubchem.ncbi.nlm.nih.gov/compound/Hydroxychloroquine#section=ClinicalTrials-gov
• Substances
• Genes for the SARS-CoV-2 virus and SARS-CoV virus and human target genes
• Proteins for the SARS-CoV-2 virus and SARS-CoV virus and human target proteins
• Enzymes (EC:2.7.7.48, EC:1.3.3.1, and EC:3.4.17.23)
• Pathways for COVID-19
• BioAssays (PubChem bioassays with title containing the keyword 'SARS')
• Taxonomy (bioassays, bioactivities, genes/proteins, pathways associated with the organism SARS-CoV-2.

Information Sources for the above PubChem lists:

• PubChem
• NCBI RefSeq
• NCBI Protein
• NCBI Structure
• NCBI GenBank
• NCBI ClinicalTrials.gov
• European Clinical Trials Register
• UniProt
• RCSB Protein DataBank (PDB)
• IUPHAR/BPS Guide to PHARMACOLOGY
• WikiPathways
• CAS COVID-19 Protein Target Thesaurus
• DrugBank
• COVID-19 Disease Map