BioAssay Record Page Released
Posted on November 24, 2015
As explained in a previous post, PubChem organizes data into three primary databases: Substance, Compound, and BioAssay. The BioAssay database contains over one million biological assay experiments containing more than 229 million bioactivity outcomes. For each assay, PubChem now provides a BioAssay Record page (formerly called the Assay Summary page), which displays information provided by the data contributor about the assay as well as annotations and links to tools that support data interpretation and analysis.
The key improvements include:
- Technology refresh
As with the recent update to the Compound Summary and the Substance Record pages, the new data-driven BioAssay interface is optimized for both touch- and mouse-based devices. Using a responsive design, it automatically adapts to the available screen size, making it friendly for desktops, tablets, and mobile phones.
- Data contents reorganized
In the new BioAssay Record page, depositor-provided information is presented first, followed by annotations based on third-party curation and PubChem processing. In the now deprecated Assay Summary page, depositor-provided information was intermingled with annotations from third-party curation and PubChem processing, often causing confusion about data provenance (i.e., the information source).
- Improved data table
While a full bioactivity data set is retrieved by default, the data table is partitioned according to activity outcomes (e.g., active, inactive, submicromolar activity, subnanomolar activity, and so on), allowing users to quickly filter results. In addition, users can download the entire data table or a filtered subset. To support comparative evaluation, a link to a cross-assay bioactivity analysis page is provided for each compound displayed in the data table.
- Extended download functionality
The top bar ‘Download’ button provides access to all downloadable data on the page. This includes depositor-provided description, data table results, chemical structures tested in an assay, and annotations shown in an individual section.
- Integrated Related BioAssay Summary
At the bottom of the BioAssay Record page, BioAssays from the same assay project and other related BioAssays are displayed in a tabular format, facilitating assay data interpretation and comparison.
- URL change
BioAssay Record page uses a different URL from the now deprecated Assay Summary page. For example, the URL for the BioAssay Record for AID 1284 is:
Links to the now deprecated Assay Summary page will automatically redirect to the new location for the BioAssay Record page.
The now deprecated Assay Summary page will remain accessible from a link at the top of the BioAssay Record page until May 2016.
A PubChem Target Summary page is in progress, helping to summarize available biological activity and annotation information in PubChem is in progress.
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